Mood Is All About Chemistry!

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And Hola may be of help ūüôā

CBD’s impact on the human body is a consequence of its interaction with the endocannabinoid system, which regulates a great part of our chemistry. These findings point at CBD’s potential to address physiological causes related to mood swings and other conditions like depression and stress.¬†

Now more than ever, the world is going through a difficult time and many of us may be subject to feelings of uneasiness and unpredictable mood swings. Moreover, the Anxiety and Depression Association of America accounted for 6.8 million people in the country suffering from General Anxiety Disorder, and 16.1 million from Major Depressive Disorder, according to Breus, M., 2018. 

These constantly increasing numbers have also caused a raise in the consumption of medications. However, most medications involve undesirable secondary effects, which is why many are in search of more natural, comprehensive alternatives.

CBD (cannabidiol) is a major compound found in the cannabis plant which has been found to have many potential benefits, both physical and mental (Crippa, J., et al., 2018). It’s important to keep in mind that differently from THC, CBD is a non-psychoactive substance, meaning that it offers the benefits of cannabis without intoxicating side effects.¬†

Most medications involve undesirable secondary effects, while CBD offers a natural and safe alternative.

CBD’s impact on the human body is a consequence of its interaction with the endocannabinoid system, which regulates a great part of our chemistry. These findings point at CBD’s potential to address physiological factors related to mood changes and other conditions like depression, anxiety, and stress (Blessing, E., et al., 2015). In the specific case of depression, scientists believe that CBD increases the response of our receptors to serotonin (Sales, A., et al., 2019); while in the case of anxiety and stress, CBD could act as a soothing substance (Zuardi, A., et al., 1993).

There are also studies that suggest CBD is a neural protector and has calming properties (Breus, M., 2018), which could positively affect our mood by relieving conditions as:

  • Insomnia

  • Chronic Pain

  • Inflammation

  • Neurological diseases

  • Autoimmune deficiencies

According to Crippa, J., et al., 2018, CBD has yielded positive results in the treatment of such conditions thanks to our CB1 and CB2 receptors. They are involved in the regulation of our central nervous system and immune system, which at the same time are responsible for pain perception, immune functions, and sleep cycles. 

When balance is reached and we’re able to rest properly, our bodies get a performance boost. This is why CBD has been used as a sleep promoter and mood stabilizer. The healthier our bodies, the healthier our minds.

Remember that if you’re under any other treatment it is vital that you consult your physician before making any changes to find what best suits your specific needs. Choose a natural alternative and your chemistry will be thankful in return.

Sources

1.- Bergamaschi, M., et al., 2011. Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-na√Įve social phobia patients. [online] Neuropsychopharmacology. <DOI:
10.1038/npp.2011.6> [Accessed 25 July 2020].

2.-Blessing, E., et al., 2015. Cannabidiol as a potential treatment for anxiety disorders. [online] Springer Link. DOI: <10.1007/s13311-015-0387-1> [Accessed 25 July 2020].

3.-Bonn-Miller, M., et al., 2017. Labeling accuracy of cannabidiol extracts sold online. [online] Jama Network. DOI: <10.1001/jama.2017.11909> [Accessed 25 July 2020].

4.-World Health Organization, 2017. Cannabidiol (CBD) pre-review report. [online] World Health Organization. Available at: <who.int/medicines/access/controlled-substances/5.2_CBD.pdf> [Accessed 25 July 2020].

5.-Zuardi, A., et al., 1993. Effects of ipsapirone and cannabidiol on human experimental anxiety. [online] Journal of Psychopharmacology.  DOI: <10.1177/026988119300700112> [Accessed 25 July 2020].

6.-Crippa, J., et al., 2018. Translational investigation of the therapeutic potential of cannabidiol (CBD): Toward a new age. [online] Frontiers. DOI: <10.3389/fimmu.2018.02009> [Accessed 25 July 2020].

7.-Darkovska-Serafimovska, M., et al., 2018. Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases. [online] Dove Press. DOI: <10.2147/JPR.S160556> [Accessed 25 July 2020].

8.-de Mello Schier, A., et al., 2014. Antidepressant-like and anxiolytic-like effects of cannabidiol: A chemical compound of cannabis sativa. [online] CBD-B. DOI: <cbd-b.be/wp-content/uploads/2018/09/2014-Antidepressant-Like-and-Anxiolytic-Like-Effects-of-Cannabidiol.pdf> [Accessed 25 July 2020].

9.-Ewing, L., et al., 2019. Hepatoxicity of a cannabidiol-rich cannabis extract in the mouse model. [online] MDPI. Available at: <mdpi.com/1420-3049/24/9/1694/htm> [Accessed 25 July 2020].

10.- Ewing, L., et al., 2019. Hepatoxicity of a cannabidiol-rich cannabis extract in the mouse model. [online] MDPI. Available at: <mdpi.com/1420-3049/24/9/1694/htm> [Accessed 25 July 2020].

11.-Martinelli, K., (n.d.). CBD What Parents Need to Know. [online] Child Mind Institute. Available at: <childmind.org/article/cbd-what-parents-need-to-knowi/> [Accessed 25 July 2020]

12.-Sales, A., et al., 2019. Cannabidiol induces rapid and sustained antidepressant-like effects through increased BDNF signaling and synaptogenesis in the prefrontal cortex. [online] Springer Link. DOI: <10.1007/s12035-018-1143-4> [Accessed 25 July 2020].

13.-Soares, V., et al., 2017. Evidences for the anti-panic actions of cannabidiol. [online] Bentham Science. DOI: <10.2174/1570159X14666160509123955> [Accessed 25 July 2020].